Space-based measurements indicate that Central Africa is a global hotspot of formaldehyde (H2CO). This is due to biomass burning and to the emissions of the vegetation itself. African megacities also suffer from poor air quality associated with the widespread use of domestic combustion for cooking and old car fleets, which lead to large amounts of PMs and NOx. Due to the rapid demographic growth, the air pollution is expected to further deteriorate in African megacities. There are thus clear interests for local measurements in megacities of Central Africa, from scientific but also public health perspectives.